A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.
Pseudomonas aeruginosa (P.aeruginosa) is an opportunistic pathogen chronically infecting the lungs of patients with chronic obstructive Pet Beds pulmonary disease (COPD), pneumonia, cystic fibrosis (CF), and bronchiectasis.Cif (PA2934), a bacterial toxin secreted in outer membrane vesicles (OMV) by P.aeruginosa, reduces CFTR-mediated chloride secre